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		<title>Why ChatGPT IS NOT Your Best Friend in Health Care</title>
		<link>https://precisionhealthalliance.org/why-gpt-is-not-your-best-friend/</link>
		
		<dc:creator><![CDATA[Zach Stumer]]></dc:creator>
		<pubDate>Fri, 19 Sep 2025 03:23:12 +0000</pubDate>
				<category><![CDATA[Articles]]></category>
		<category><![CDATA[Business]]></category>
		<category><![CDATA[Coaching]]></category>
		<category><![CDATA[Precision Health]]></category>
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		<category><![CDATA[environment]]></category>
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		<guid isPermaLink="false">https://precisionhealthalliance.org/?p=15330</guid>

					<description><![CDATA[by Dr Cam McDonald AI is everywhere. From writing emails to planning workouts, tools like ChatGPT make life easier. It’s tempting to ask them for health advice too. But when [&#8230;]]]></description>
										<content:encoded><![CDATA[<p><span style="font-weight: 400;">by Dr Cam McDonald</span></p>
<p><span style="font-weight: 400;">AI is everywhere. From writing emails to planning workouts, tools like ChatGPT make life easier. It’s tempting to ask them for health advice too. But when the goal is a longer, healthier life, </span><b>the kind of AI you choose makes all the difference</b><span style="font-weight: 400;">.</span></p>
<p><span style="font-weight: 400;">Let’s look at why a popular generalist like ChatGPT can be helpful—but falls short for true personalised care—and how CLIA, working inside the Shae precision-health platform, sets a completely different standard.</span></p>
<h2><b>ChatGPT: Brilliant Wordsmith, Limited Health Guide</b></h2>
<p><span style="font-weight: 400;">ChatGPT is a </span><i><span style="font-weight: 400;">language</span></i><span style="font-weight: 400;"> expert. It has learned patterns from billions of pages of text—articles, books, medical papers and everyday conversations. That training lets it explain complex ideas clearly and even follow multi-step reasoning.</span></p>
<p><span style="font-weight: 400;">It can:</span></p>
<ul>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Translate research into everyday language</span></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Summarise long guidelines</span></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Draft patient emails or clinic handouts</span><span style="font-weight: 400;">
<p></span></li>
</ul>
<p><span style="font-weight: 400;">Where it stops short is </span><b>knowing you</b><span style="font-weight: 400;">.</span><span style="font-weight: 400;"><br />
</span><span style="font-weight: 400;"> Unless a custom patient model is built on top, ChatGPT does not keep a living, causal map of your unique biology. Two people can type in the same blood results and get almost identical advice—even if their underlying risks, genetics and daily rhythms are worlds apart.</span></p>
<p><span style="font-weight: 400;">It’s not that ChatGPT is careless. It does have safety policies. But those rules are broad and not medically specific. They help avoid obvious harm; they don’t provide the deep, personalised guardrails that clinical care demands.</span></p>
<h2><b>CLIA/Shae: Designed to Know the Person, Not Just the Problem</b></h2>
<p><span style="font-weight: 400;">CLIA (Clinical Lab Interpretation AI) was created with one goal: </span><b>precision medicine</b><span style="font-weight: 400;">.</span><span style="font-weight: 400;"><br />
</span><span style="font-weight: 400;"> It isn’t a general chatbot that happens to talk about health. It’s a precision-health engine built from the ground up to understand each individual and predict how their body will respond over time.</span></p>
<p><span style="font-weight: 400;">CLIA works by:</span></p>
<ul>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Integrating </span><b>phenotype, genotype, bloods, imaging, microbiome data, lifestyle habits, and wearable inputs</b><b>
<p></b></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Modelling </span><b>cross-system interactions</b><span style="font-weight: 400;"> like gut–immune–neuroendocrine loops and cardio–renal links</span><span style="font-weight: 400;">
<p></span></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Forecasting what will change over the next 6–12 months and adjusting recommendations as new information flows in</span><span style="font-weight: 400;">
<p></span></li>
</ul>
<p><span style="font-weight: 400;">Every output is </span><b>clinically supervised</b><span style="font-weight: 400;">. A specialist panel and evidence-based guidelines define what CLIA can and cannot recommend. If a plan could put health at risk, the system won’t bend to pressure—it simply won’t suggest it.</span></p>
<h2><b>Real-Life Scenarios Show the Difference</b></h2>
<p><b>Gene confusion, like MTHFR variants</b><b><br />
</b><span style="font-weight: 400;"> In online forums, people often wonder whether to take methylfolate based on a single gene result. ChatGPT can explain the pathway and urge caution, but it cannot weigh that gene against full blood panels, medications, diet, stress and lifestyle. CLIA brings all of those pieces together before giving an answer.</span></p>
<p><b>Rare but serious conditions</b><b><br />
</b><span style="font-weight: 400;"> Consider gadolinium deposition disease, a rare complication of MRI contrast. CLIA can link MRI history with neurological symptoms, lab trends and phenotype, raising GDD as a possible issue and suggesting the right next tests. ChatGPT could describe the condition but would not rank it for that particular person.</span></p>
<p><b>Two patients, same labs</b><b><br />
</b><span style="font-weight: 400;"> Imagine two people with the same BMI and similar cholesterol numbers. ChatGPT might provide the same diet advice to both. CLIA will not. It can spot differences in circadian rhythm, food timing tolerance and stress load, then create unique plans with different forecasts for each.</span></p>
<p><b>Critical red flags</b><b><br />
</b><span style="font-weight: 400;"> A cholesterol reading around 500 mg/dL is a genuine emergency. ChatGPT will recommend immediate medical care—good. CLIA goes further: preparing a concise referral summary, flagging phenotypic risk modifiers and suggesting safe interim steps while urgent care is arranged.</span></p>
<h2><b>Built on Big, Meaningful Data</b></h2>
<p><span style="font-weight: 400;">Precision medicine only works with deep and trustworthy data. CLIA’s engine is fed by:</span></p>
<ul>
<li style="font-weight: 400;" aria-level="1"><b>Volume</b><span style="font-weight: 400;"> – decades of carefully collected, clinically supervised person-level data representing an incredible amount of human follow up data</span></li>
<li style="font-weight: 400;" aria-level="1"><b>Variety</b><span style="font-weight: 400;"> – contributions from 140 countries for broad, bias-resistant insights</span><span style="font-weight: 400;">
<p></span></li>
<li style="font-weight: 400;" aria-level="1"><b>Veracity</b><span style="font-weight: 400;"> – every data stream reviewed and quality-checked by medical experts</span><span style="font-weight: 400;">
<p></span></li>
</ul>
<p><span style="font-weight: 400;">These foundations let CLIA create precision reference ranges for each person—something generic AI simply cannot do.</span></p>
<h2><b>Proven Impact</b></h2>
<p><span style="font-weight: 400;">Technology is only as good as the outcomes it delivers. Independent audits and internal studies show that people using the Shae app powered by CLIA experience:</span></p>
<ul>
<li style="font-weight: 400;" aria-level="1"><b>Lowered risk of cardiovascular disease and type 2 diabetes</b><span style="font-weight: 400;"> through targeted lifestyle changes</span><span style="font-weight: 400;">
<p></span></li>
<li style="font-weight: 400;" aria-level="1"><b>Reduced risk of mental health issues</b><span style="font-weight: 400;"> in workplace populations thanks to precision coaching</span></li>
</ul>
<p><span style="font-weight: 400;">This is real-world evidence that personal data, when analysed correctly, can lead to measurable improvements in health and well-being.</span></p>
<h2><b>Privacy and Professionalism at the Core</b></h2>
<p><span style="font-weight: 400;">Health data deserves the highest level of care. CLIA stores all identifiable information, including genomic and wearable inputs, in secure, closed systems that meet or exceed Australian and international privacy standards. Users know how their data is used and can opt out at any time.</span></p>
<p><span style="font-weight: 400;">Equally important, CLIA is </span><b>not a diagnostic tool</b><span style="font-weight: 400;">. It supports doctors, allied health providers and health coaches by providing a comprehensive review of each person’s data, leaving the clinician firmly in charge of decisions.</span></p>
<h2><b>Where Each AI Fits</b></h2>
<p><span style="font-weight: 400;">The takeaway isn’t to avoid ChatGPT entirely. It shines in areas like:</span></p>
<ul>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Education and translation of medical language</span></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Summarising new research for busy practitioners</span></li>
<li style="font-weight: 400;" aria-level="1"><span style="font-weight: 400;">Brainstorming discussion questions for clinic visits</span></li>
</ul>
<p><span style="font-weight: 400;">Use it for knowledge and communication.</span><span style="font-weight: 400;"><br />
</span><span style="font-weight: 400;"> Use </span><b>CLIA/Shae</b><span style="font-weight: 400;"> for individualised health planning and precision decision support.</span></p>
<h2><b>The Future of Health Is Personal</b></h2>
<p><span style="font-weight: 400;">We all want convenient tools. It’s natural to ask a free online AI about diet or symptoms. But </span><b>health is not one-size-fits-all</b><span style="font-weight: 400;">. Your genes, microbiome, daily rhythms and environment create a unique blueprint. Acting on generalised answers can delay the care you truly need.</span></p>
<p><span style="font-weight: 400;">Choosing CLIA inside the Shae platform means choosing AI that </span><i><span style="font-weight: 400;">knows the person, not just the problem</span></i><span style="font-weight: 400;">. It translates complex science into practical, personalised guidance with proven outcomes.</span></p>
<h3><b>Bottom Line</b></h3>
<p><span style="font-weight: 400;">ChatGPT is a powerful companion for learning. CLIA/Shae is a trusted partner for living well.</span><span style="font-weight: 400;"><br />
</span><span style="font-weight: 400;"> When it comes to your health, choose the AI designed for precision medicine—and step into the future of care that understands </span><i><span style="font-weight: 400;">you</span></i><span style="font-weight: 400;">.</span></p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">15330</post-id>	</item>
		<item>
		<title>Transforming Client Outcomes with the Secret Ws of Food</title>
		<link>https://precisionhealthalliance.org/transforming-client-outcomes-with-the-secret-ws-of-food/</link>
		
		<dc:creator><![CDATA[Melinda Perkins]]></dc:creator>
		<pubDate>Fri, 10 Jan 2025 18:52:56 +0000</pubDate>
				<category><![CDATA[Articles]]></category>
		<category><![CDATA[Nutrition]]></category>
		<category><![CDATA[Precision Health]]></category>
		<category><![CDATA[allied health]]></category>
		<category><![CDATA[certified health coach]]></category>
		<category><![CDATA[Certified Personal Trainer]]></category>
		<category><![CDATA[chronobiology]]></category>
		<category><![CDATA[dietician]]></category>
		<category><![CDATA[environment]]></category>
		<category><![CDATA[epigenetics]]></category>
		<category><![CDATA[fitness coaching]]></category>
		<category><![CDATA[fitness education]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[genetics]]></category>
		<category><![CDATA[health and wellness]]></category>
		<category><![CDATA[nutrition]]></category>
		<category><![CDATA[nutrition coach]]></category>
		<category><![CDATA[online education]]></category>
		<category><![CDATA[personalization]]></category>
		<category><![CDATA[personalized health]]></category>
		<category><![CDATA[precision health]]></category>
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		<guid isPermaLink="false">https://precisionhealthalliance.org/?p=13725</guid>

					<description><![CDATA[by Melinda Perkins “I have my food dialed in.”  No matter your niche in the health industry, sooner or later, you’re going to hear these words from a client. This [&#8230;]]]></description>
										<content:encoded><![CDATA[<p><span style="font-weight: 400">by Melinda Perkins</span></p>
<p><span style="font-weight: 400">“I have my food dialed in.” </span></p>
<p><span style="font-weight: 400">No matter your niche in the health industry, sooner or later, you’re going to hear these words from a client. This is the client who can list the latest Superfoods off the top of their head (and get the spelling and pronunciation right, too). They rattle off the top sources of vitamin B on their plates as well as the six different podcasts that proclaim the “worst” food of the minute. (Which they categorically avoid).</span></p>
<p><span style="font-weight: 400">To their knowledge, they have conquered the frontier of food. Yet they are baffled as to why they can’t summon the energy of a teen, can’t shed those pesky last 5 pounds or can’t get their tummy to shut up after lunch.</span></p>
<p><span style="font-weight: 400">The fact is, they’ve just scratched the surface of the first W of food: What’s on their plate. And they’re probably leaving the most important aspects of the food picture on the table (pun intended). </span></p>
<p><span style="font-weight: 400">Let’s be honest, life isn’t lived in a vacuum of perfectly balanced Superfood salads.</span><span style="font-weight: 400"></p>
<p></span></p>
<p><span style="font-weight: 400">If you peered in on their lunchtime routine, it looks like this: </span></p>
<p><span style="font-weight: 400">The clock hits noonish and they randomly thrust one hand into their triple-insulated YETI lunch bag, while furiously typing an email with the other. They’re snarling, either at the screen or because their fingertips can’t blindly find their fork; or both. Fast forward a few minutes. The snarls are equally mingled with ferocious chomping as they decimate that perfectly configured Superfood Salad, eyes still glued to the computer screen, mind still lasered-in on the latest drama unfolding in cyberspace. </span></p>
<p>&nbsp;</p>
<h2><b>Enter the first secret W of food: Where</b></h2>
<p><span style="font-weight: 400">Now imagine your client savoring the decadence of that same power packed lunch on a quiet park bench with a side of fresh air and a backdrop of babbling brook. Feels different, right? </span></p>
<p><span style="font-weight: 400">The body thinks so, too.</span></p>
<p><span style="font-weight: 400">Stress, whether it’s the overt kind with infuriating emails, ringing phones and irate customers or the background hum they’ve learned to live with, does more than dampen digestion; it can actually impair nutrient absorption. When cortisol takes the wheel, their body isn’t focused on thriving, it merely wants to survive.</span></p>
<p><span style="font-weight: 400">So, simply tell your client to reserve a park bench at mid day and all their troubles will be carried away on the lilt of birdsong, right?</span></p>
<p><span style="font-weight: 400">If only it were that simple.</span></p>
<p><span style="font-weight: 400">What launches one client into stress could be exactly what another needs to relax into rest and digest. It’s all shaped by their unique physiological and sensory needs. Some people thrive in calm, minimalistic spaces, while others find relaxation in lively, bright, even noisy surroundings. A sunny park bench could be the perfect dining haven or a nightmare of glaring light, scents on the breeze and uninvited flying things.</span></p>
<p><span style="font-weight: 400">So what’s the trick to this W?</span></p>
<p><span style="font-weight: 400">Precision. Encourage your client to grab that illusive fork and superlative salad and seek out their ideal dining sanctuary. Creating an intentional eating space, tailored to their individual needs is next level nutrition. It’s a small shift that can lead to big improvements in digestion, satiety, and even mood.</span></p>
<p>&nbsp;</p>
<p><span style="font-weight: 400">Fantastic, your client is no longer balancing their salad in one hand and typing with the other. But as they settle into their serene eating environment, another question arises: Who is sitting next to them? Or perhaps, who isn’t?</span></p>
<p>&nbsp;</p>
<h2><b>Food and Friends: The Secret of Who</b></h2>
<p><span style="font-weight: 400">Sharing meals isn’t just a tradition; it’s hardwired into our biology. Eating together naturally activates the parasympathetic nervous system, which is precisely what we’re aiming for to get all those Superfood molecules to reach their right destination. </span></p>
<p><span style="font-weight: 400">Enter real-life. </span></p>
<p><span style="font-weight: 400">Especially if your client is busy (and who isn’t?), meals are reduced to stolen moments of grabbing and chomping. It’s one thing to carve out a tiny optimized corner to gobble down some greens, but completely another to set up your social calendar around your stomach. </span></p>
<p><span style="font-weight: 400">That’s precisely why this is next level because the fact is WHO your client eats with can shape their entire dining experience and their digestion, absorption and wait….</span></p>
<p><span style="font-weight: 400">Even the original W: What! </span></p>
<p><span style="font-weight: 400">Your clients don’t just bring their own habits to the table, they pick up on those of their dining companions. Social mirroring is a powerful, often subconscious force.</span></p>
<p><span style="font-weight: 400">When clients eat with health-conscious peers, they’re more likely to make better choices themselves. A meal with friends who load their plates with nutrient-dense foods can subliminally encourage your client to do the same. Conversely, indulgent social settings (think all-you-can-eat buffets or celebratory feasts with an “anything goes” vibe) may divest them completely of their dreams of better health.</span></p>
<p><span style="font-weight: 400">Great, so now you’re tasked with culling their contacts list like a helicopter parent?</span></p>
<p><span style="font-weight: 400">On the contrary, while sharing this insider W might just make you their go-to expert to completely reshape their relationship with food, all you have to do is help them make it personal. </span></p>
<p><span style="font-weight: 400">Just like that perfect “Where”, The right &#8216;who&#8217; looks different for everyone. Some clients recharge with joyful, communal meals brimming with conversation, while others need a quiet moment with one close friend, or the peace of complete solitude. Your mission? Guide them to discover which social dynamics foster the balance and support they need. </span></p>
<p>&nbsp;</p>
<p><span style="font-weight: 400">Alright, they’ve got their dream team at the table (or they’re flying solo on that peaceful park bench). Let’s make a powerful impact with the King of the Titans: Chronos</span></p>
<h2><b>Cracking the Code: The Secret of When</b></h2>
<p><a href="https://precisionhealthalliance.org/what-is-chronobiology/"><span style="font-weight: 400">Chronobiology, the study of biological rhythms</span></a><span style="font-weight: 400">, reveals the profound influence of time on digestion, metabolism, and overall health. Meals consumed in sync with the body’s natural cycles honor the wisdom of Chronos, optimizing function and reducing stress on the system.</span></p>
<p><span style="font-weight: 400">This isn’t about hurriedly gulping down a smoothie between battles with your inbox, it’s about unlocking the full potential of nutrition, and letting time work for you, not against you.</span></p>
<p><span style="font-weight: 400">When clients eat out of sync with their internal clocks a phenomenon called chronobiological dyssynchrony occurs. It disrupts digestion, metabolism, and hormonal balance, increasing risks for inflammation, metabolic disorders, and chronic diseases. Even subtle misalignments, like eating a heavy meal late at night, can strain the body, causing fatigue, weight gain or those illusive belly groans and gurgles.</span></p>
<p><span style="font-weight: 400">Here’s where things get even more exciting: not all clients operate on the same chronobiological blueprint. Some thrive on a hearty breakfast and feel energized all morning, while others perform best with lighter morning meals and a robust lunch. Helping clients identify their optimal eating windows and pair them with perfect portions sets the foundation for every other health goal on their list.</span></p>
<h2><strong>From Insights to Action: The Ws Made Easy</strong></h2>
<p><span style="font-weight: 400">Your client who has their “food dialed-in” doesn’t need another list of Superfoods, they need a health professional who sees the whole picture. The </span><i><span style="font-weight: 400">where,</span></i> <i><span style="font-weight: 400">who,</span></i><span style="font-weight: 400"> and </span><i><span style="font-weight: 400">when</span></i><span style="font-weight: 400"> of eating offer the missing pieces to their health puzzle, and put them on the path to achieve the energy, balance, and health they’ve been striving for.</span></p>
<p><span style="font-weight: 400">And here’s the good news: using science-backed AI technologies to enhance your practice means you don’t have to figure it all out alone. You can seamlessly integrate the latest in every nutrition W (including the What, Why and How) with your expertise to easily deliver precise, individualized strategies for every client.</span></p>
<h3><strong>Ready to redefine what’s possible for your clients? </strong></h3>
<p><span style="font-weight: 400">Bring the science of </span><i><span style="font-weight: 400">when,</span></i> <i><span style="font-weight: 400">where,</span></i> <i><span style="font-weight: 400">who</span></i><span style="font-weight: 400"> and more to life in your practice with our </span><a href="https://precisionhealthalliance.org/course-pha-level-1/"><span style="font-weight: 400">Level 1 Course for Health Professionals</span></a><span style="font-weight: 400">.</span></p>
<p>&nbsp;</p>
]]></content:encoded>
					
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">13725</post-id>	</item>
		<item>
		<title>What is Chronobiology?</title>
		<link>https://precisionhealthalliance.org/what-is-chronobiology/</link>
					<comments>https://precisionhealthalliance.org/what-is-chronobiology/#respond</comments>
		
		<dc:creator><![CDATA[Melinda Perkins]]></dc:creator>
		<pubDate>Fri, 31 May 2024 19:46:29 +0000</pubDate>
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		<category><![CDATA[chronobiology]]></category>
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		<guid isPermaLink="false">https://precisionhealthalliance.org/?p=11099</guid>

					<description><![CDATA[By Melinda Perkins &#8211;    Circadian Rhythm.   Biological Rhythm.    Body Clocks. We’ve heard the words. We might use them in casual conversation. We might even preach to our clients the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p><span style="font-weight: 400;">By Melinda Perkins &#8211;   </span></p>
<p><strong>Circadian Rhythm.   Biological Rhythm.    Body Clocks.</strong></p>
<p><span style="font-weight: 400;">We’ve heard the words. We might use them in casual conversation. We might even preach to our clients the importance of them. But if put on the spot, would we be able to accurately and specifically define them? How about effectively adding them into a program or workup for our patients or clients?</span></p>
<p><span style="font-weight: 400;">All of those words and more stem from the overarching area of Chronobiology.</span></p>
<p><strong>Would it surprise you to learn that you could supercharge your client’s results just by sprinkling in a bit of timing know-how?</strong></p>
<h2><span style="font-weight: 400;">Let’s take a look:</span></h2>
<p><span style="font-weight: 400;">Chronobiology is a multidisciplinary field of study where scientists research the rhythms of living organisms. Oddly, prior to the last few decades, much of the work revolved around plants. Since it branched out to animals, and finally humans, our understanding of the effects of the physical, solar, lunar and environmental cycles has skyrocketed. </span></p>
<p><strong>Here’s the rundown.</strong></p>
<p><span style="font-weight: 400;">As humans, we have a circadian master clock which runs on a 24 hour cycle based on light and dark information. This clock resets when sunlight hits the eye. That’s why blue light limitation has become so popular for maintaining our sleep cycles, and thus, our better health. </span></p>
<p><span style="font-weight: 400;">So, we have this master clock which is a group of cells called the</span><a href="https://pubmed.ncbi.nlm.nih.gov/8047576/"><span style="font-weight: 400;"> suprachiasmatic nucleus (SCN) </span></a><span style="font-weight: 400;">housed in the hypothalamus of the brain. As it goes, when we name something the “master”, it usually follows that there are other pieces of the puzzle which are less masterful. This is no different with our body clocks</span></p>
<p><span style="font-weight: 400;">These “less-masterful” entities are called peripheral clocks and reside in every tissue in the body. They oversee things like insulin release, fat storage, energy production and body temperature. Many of them both receive as well as send messages back to the SCN. All of them interact with our behaviors and the environment around us such as food intake, physical movement and body temperature. Among other things, they wake us up, send us to sleep, make us grow, tell our bodies to recover, assist movement, and help us digest.</span></p>
<h2><span style="font-weight: 400;">Why do we care?</span></h2>
<p><span style="font-weight: 400;">Okay, we’re talking clocks, right? </span></p>
<p><span style="font-weight: 400;">Lots of clocks. </span></p>
<p><span style="font-weight: 400;">Imagine an entire shop filled with hundreds of clocks. When they tick along in sync with each other under the direction of the master clock, the shop is filled with a melodious tick-tock song. When one or two get behind, it’s distracting to the ear. Add in a few more and the cacophony will send you running out the door. </span></p>
<p><span style="font-weight: 400;">In our bodies this chaos is called </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261021/#:~:text=The%20relationship%20between%20circadian%20disruption%20and%20human%20health,often%20preceding%20the%20classical%20symptoms%20of%20neurodegenerative%20disorders."><span style="font-weight: 400;">circadian desynchrony (CD).</span></a><span style="font-weight: 400;"> Obviously, this is not a desirable state of being in a body that strives for homeostasis, balance and harmony.</span></p>
<h3><strong>Let’s talk about you…</strong></h3>
<p><span style="font-weight: 400;">Whether you realize it or not, you probably use chronobiology every day. Think about any client you have. When they first walked through your door, you noticed many things in an instant including their age and what they were wearing.</span></p>
<p><span style="font-weight: 400;">Their age told you of their journey through the years. (Circannual rhythm.) </span></p>
<p><span style="font-weight: 400;">Clothing (and a glance out the window) told you of the season. Both of these fall in the category of chronobiology called infradian rhythms which have a cycle of more than 24 hours (monthly biannually or yearly) </span></p>
<p><span style="font-weight: 400;">You invite them to sit down and you discover a bit more. You might ask about their eating habits, energy levels and what kind of work and exercise they do. From those things you know their rhythms of digestion, hormone release, productivity/focus, and energy production.</span></p>
<p><span style="font-weight: 400;">These are a second aspect of chronobiology called Ultradian cycles or things that happen multiple times in a 24 hour period. </span></p>
<p><span style="font-weight: 400;">And lastly you might ask about their sleep and wake cycles. These bring us back to that 24 hour circadian rhythm and the all-important master clock.</span></p>
<h3><strong>Here’s what you might be missing:</strong></h3>
<p><span style="font-weight: 400;">Still thinking of that client…</span></p>
<p><span style="font-weight: 400;">What might not be outwardly apparent is that most people on the planet since the invention of the lightbulb are desynchronized with their master clock due to artificial light. Add to that a few irregular meal times, some weird sleep patterns and even an air conditioner over their desk at work and their internal clock shop sounds like a 5th grade orchestra warming up. Not only does the noise make you want to run for the hills, desynchronization has been correlated to everything from </span><a href="https://www.mdpi.com/1422-0067/20/7/1597/htm"><span style="font-weight: 400;">metabolic disease</span></a><span style="font-weight: 400;"> to </span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026420/"><span style="font-weight: 400;">neurological disorders</span></a><span style="font-weight: 400;"> to </span><a href="https://www.frontiersin.org/articles/10.3389/fendo.2018.00219/full"><span style="font-weight: 400;">cancer.</span></a><span style="font-weight: 400;"> </span></p>
<h2><span style="font-weight: 400;">What can you do about it?</span></h2>
<p><strong>Meet the givers of time: …light…food…exercise</strong></p>
<p><span style="font-weight: 400;">Okay, we’ve established that timing is everything. We have the master clock that sets the rhythm based on light. Then we have our peripheral clocks that listen to the master clock, but they also take cues from our behavior; how we eat and exercise. </span></p>
<p><span style="font-weight: 400;">Back to our clock shop.</span></p>
<p><span style="font-weight: 400;">The tissues involved in digestion (stomach, endocrine, gut, etc.) have an optimal operating rhythm that is in sync with the master clock. When an individual eats at those specific times, the digestive system is ready to work and everything is primed for performance. Digestion is super efficient, delivery of nutrients to tissues is optimal, energy production is peak.</span></p>
<p><span style="font-weight: 400;">The result is a bevy of clocks in sync which is a beautiful thing!</span></p>
<p><span style="font-weight: 400;">But say, we </span><a href="https://diabetesjournals.org/care/article/40/11/1573/36945/Influences-of-Breakfast-on-Clock-Gene-Expression"><span style="font-weight: 400;">skip meals and have midnight snacks</span></a><span style="font-weight: 400;">. Skipping meals tells the body a story of scarcity (not a great thing unless you want to pack on the pounds). Then, that doughnut at midnight sets off a series of events. Not only is the digestive system not primed for food, but the alarms go off and the tissues report back to the master clock that it’s daytime. The master clock, getting its information from the eye says, “Nope.”. Suddenly our clocks are out of sync. </span></p>
<p><span style="font-weight: 400;">Same goes with </span><a href="https://www.pnas.org/doi/full/10.1073/pnas.1006749107"><span style="font-weight: 400;">exercise</span></a><span style="font-weight: 400;">.</span></p>
<p><span style="font-weight: 400;">Studies show that if you </span><a href="https://journals.lww.com/acsm-msse/Abstract/1985/10000/Circadian_rhythms_and_athletic_performance.2.aspx"><span style="font-weight: 400;">exercise out of sync with your natural rhythm</span></a><span style="font-weight: 400;">, it actually has adverse effects like increased insulin resistance, decreased focus and coordination leading to higher possibilities of injury and even </span><a href="https://journals.physiology.org/doi/full/10.1152/ajpregu.00355.2002"><span style="font-weight: 400;">delayed melatonin release</span></a><span style="font-weight: 400;">.</span></p>
<h3><strong>But how do you line up those clocks?</strong></h3>
<p><span style="font-weight: 400;">Here’s where true personalization comes in:</span></p>
<p><span style="font-weight: 400;">As a health professional, you already recognize that every client is an individual with different histories, present habits and future goals. What the study of chronobiology adds is that each person is endowed with a unique set of rhythms.  Their clocks tick in a completely personal way. Therefore, synchrony creates a distinctive song in each body. </span></p>
<h3><strong>What does this mean?</strong></h3>
<p><span style="font-weight: 400;">Every person has certain times in the day where they perform mental tasks better or are more ready to move or digest. Add to that the times of day when they most need to socialize or be in nature or rest and the possibilities for pinpointing the precise intervention for that specific person unfold. When you understand the chronobiology of a client, you get a glimpse into the timing of their hormone release. Then, you can synchronize specific activities with the correct hormone release for that task and BAM! Success is simple!</span></p>
<p><strong>Let’s get specific:</strong></p>
<p><span style="font-weight: 400;">Say your client’s cortisol peaks super fast in the morning and their body temp is up super quick after rising. Essentially, they are ready for action. If you recommend exercise, hard mental tasks and complex productivity steps early in the day, they will ride the wave of their hormones, thus working with their natural rhythms.</span></p>
<p><span style="font-weight: 400;">Another client’s melatonin sticks around a bit longer in the morning, pushing that cortisol peak later in the day. These things, along with a natural drop in insulin sensitivity and greater cardiovascular efficiency in the afternoon, prime them for a trip to the gym later in the day.</span></p>
<p><span style="font-weight: 400;">And this is just the beginning. There are as many configurations as there are hormones in the body and people who walk in the door of your practice. </span></p>
<p><strong>But the same caveat applies: </strong></p>
<p><span style="font-weight: 400;">When your program harnesses the power of clocks ticking in sync, your clients feel strong, strive toward their goals with ease, enjoy life more and stick to it. They excel…and all things improve.</span></p>
<h2><span style="font-weight: 400;">A final note:</span></h2>
<p><span style="font-weight: 400;">Our desire is to create the perfect plan for each client to achieve their desired results in the shortest amount of time possible with the least effort expended. That is true efficiency. Adding the chronobiological component into our already effective programs takes our client/practitioner success to the next level. And who doesn’t want to do that?</span></p>
<p>&nbsp;</p>
<p><span style="font-weight: 400;">To learn how to apply precision methods and technology solutions to your service offering and effectively add chronobiology and more to your practice, check out our </span><a href="https://precisionhealthalliance.org/course-pha-level-1/"><span style="font-weight: 400;">Level 1 Course for Health Professionals</span></a><span style="font-weight: 400;">.</span></p>
<p>&nbsp;</p>
<p><b>References</b></p>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261021/#:~:text=The%20relationship%20between%20circadian%20disruption%20and%20human%20health,often%20preceding%20the%20classical%20symptoms%20of%20neurodegenerative%20disorders."><span style="font-weight: 400;">Circadian disruption and human health: A bidirectional relationship &#8211; PMC (nih.gov)</span></a><span style="font-weight: 400;"> </span></p>
<p><span style="font-weight: 400;">Abbott SM, Malkani RG, Zee PC. Circadian disruption and human health: A bidirectional relationship. </span><i><span style="font-weight: 400;">Eur J Neurosci</span></i><span style="font-weight: 400;">. 2020;51(1):567-583. doi:10.1111/ejn.14298</span></p>
<p><span style="font-weight: 400;">Article with tons of notations on studies of circadian desynchrony </span></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/8047576/"><span style="font-weight: 400;">The suprachiasmatic nucleus controls the circadian rhythm of heart rate via the sympathetic nervous system &#8211; PubMed (nih.gov)</span></a></p>
<p><span style="font-weight: 400;">Warren WS, Champney TH, Cassone VM. The suprachiasmatic nucleus controls the circadian rhythm of heart rate via the sympathetic nervous system. Physiol Behav. 1994 Jun;55(6):1091-9. doi: 10.1016/0031-9384(94)90392-1. PMID: 8047576.</span></p>
<p><a href="https://www.pnas.org/doi/full/10.1073/pnas.1006749107"><span style="font-weight: 400;">https://www.pnas.org/doi/full/10.1073/pnas.1006749107</span></a></p>
<p><span style="font-weight: 400;">Christian Cajochen, Jakob Weber, Alejandro F. Estrada,Kumpei Kobayashi,Virginie Gabel,</span></p>
<p><span style="font-weight: 400;">Circadian and homeostatic sleep-wake regulation of secretory immunoglobulin A (sIgA): Effects of environmental light and recovery sleep, Brain, Behavior, &amp; Immunity &#8211; Health, 19, (100394), (2022).</span></p>
<p><a href="https://doi.org/10.1016/j.bbih.2021.100394"><span style="font-weight: 400;">https://doi.org/10.1016/j.bbih.2021.100394</span></a></p>
<p><span style="font-weight: 400;">Impact of the human circadian system, exercise, and their interaction on cardiovascular function</span></p>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026420/"><span style="font-weight: 400;">Circadian rhythm disruption and mental health &#8211; PMC (nih.gov)</span></a></p>
<p><span style="font-weight: 400;">Walker WH 2nd, Walton JC, DeVries AC, Nelson RJ. Circadian rhythm disruption and mental health. </span><i><span style="font-weight: 400;">Transl Psychiatry</span></i><span style="font-weight: 400;">. 2020;10(1):28. Published 2020 Jan 23. doi:10.1038/s41398-020-0694-0</span></p>
<p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0306452210011103?via%3Dihub"><span style="font-weight: 400;">https://www.sciencedirect.com/science/article/abs/pii/S0306452210011103?via%3Dihub</span></a></p>
<ol>
<li><span style="font-weight: 400;"> Shuboni, L. Yan,</span></li>
</ol>
<p><span style="font-weight: 400;">Nighttime dim light exposure alters the responses of the circadian system,</span></p>
<p><span style="font-weight: 400;">Neuroscience,Volume 170, Issue 4,2010, Pages 1172-1178,  ISSN 0306-4522,</span></p>
<p><span style="font-weight: 400;">https://doi.org/10.1016/j.neuroscience.2010.08.009.</span></p>
<p><a href="https://academic.oup.com/jcem/article-abstract/106/3/e1373/5922806?redirectedFrom=fulltext&amp;login=false"><span style="font-weight: 400;">https://academic.oup.com/jcem/article-abstract/106/3/e1373/5922806?redirectedFrom=fulltext&amp;login=false</span></a></p>
<p><span style="font-weight: 400;">Leilah K Grant, Charles A Czeisler, Steven W Lockley, Shadab A Rahman, Time-of-day and Meal Size Effects on Clinical Lipid Markers, </span><i><span style="font-weight: 400;">The Journal of Clinical Endocrinology &amp; Metabolism</span></i><span style="font-weight: 400;">, Volume 106, Issue 3, March 2021, Pages e1373–e1379, </span></p>
<p><span style="font-weight: 400;">Time-of-day and Meal Size Effects on Clinical Lipid Markers </span></p>
<p><a href="https://diabetesjournals.org/care/article/40/11/1573/36945/Influences-of-Breakfast-on-Clock-Gene-Expression"><span style="font-weight: 400;">https://diabetesjournals.org/care/article/40/11/1573/36945/Influences-of-Breakfast-on-Clock-Gene-Expression</span></a></p>
<p><span style="font-weight: 400;">Daniela Jakubowicz, Julio Wainstein, Zohar Landau, Itamar Raz, Bo Ahren, Nava Chapnik, Tali Ganz, Miriam Menaged, Maayan Barnea, Yosefa Bar-Dayan, Oren Froy; Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial. </span><i><span style="font-weight: 400;">Diabetes Care</span></i><span style="font-weight: 400;"> 1 November 2017; 40 (11): 1573–1579.</span></p>
<p><a href="https://journals.physiology.org/doi/full/10.1152/ajpregu.00355.2002"><span style="font-weight: 400;">https://journals.physiology.org/doi/full/10.1152/ajpregu.00355.2002</span></a></p>
<p><span style="font-weight: 400;">Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase</span></p>
<p><span style="font-weight: 400;">Orfeu M. Buxton, Calvin W. Lee, Mireille L&#8217;Hermite-Balériaux, Fred W. Turek, and Eve Van Cauter</span></p>
<p><span style="font-weight: 400;">American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2003 284:3, R714-R724</span><span style="font-weight: 400;">   </span></p>
<p><a href="https://www.mdpi.com/1422-0067/20/7/1597/htm"><span style="font-weight: 400;">https://www.mdpi.com/1422-0067/20/7/1597/htm</span></a></p>
<p><span style="font-weight: 400;">Maury, E. Off the Clock: From Circadian Disruption to Metabolic Disease. </span><i><span style="font-weight: 400;">Int. J. Mol. Sci.</span></i> <b>2019</b><span style="font-weight: 400;">, </span><i><span style="font-weight: 400;">20</span></i><span style="font-weight: 400;">, 1597. https://doi.org/10.3390/ijms20071597</span></p>
<p><span style="font-weight: 400;"> </span></p>
<p><span style="font-weight: 400;"> </span><a href="https://journals.lww.com/acsm-msse/Abstract/1985/10000/Circadian_rhythms_and_athletic_performance.2.aspx"><span style="font-weight: 400;">Circadian rhythms and athletic performance : Medicine &amp; Science in Sports &amp; Exercise (lww.com)</span></a></p>
<p><span style="font-weight: 400;">WINGET, CHARLES M.; DEROSHIA, CHARLES W.; HOLLEY, DANIEL C. Circadian rhythms and athletic performance, Medicine &amp; Science in Sports &amp; Exercise: October 1985 &#8211; Volume 17 &#8211; Issue 5 &#8211; p 498-516</span></p>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530273/"><span style="font-weight: 400;">RELATIONSHIP OF ENDOGENOUS CIRCADIAN MELATONIN AND TEMPERATURE RHYTHMS TO SELF-REPORTED PREFERENCE FOR MORNING OR EVENING ACTIVITY IN YOUNG AND OLDER PEOPLE &#8211; PMC (nih.gov)</span></a></p>
<p><span style="font-weight: 400;">Duffy JF, Dijk DJ, Hall EF, Czeisler CA. Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people. </span><i><span style="font-weight: 400;">J Investig Med</span></i><span style="font-weight: 400;">. 1999;47(3):141-150.</span></p>
<p><a href="https://www.frontiersin.org/articles/10.3389/fendo.2018.00219/full"><span style="font-weight: 400;">https://www.frontiersin.org/articles/10.3389/fendo.2018.00219/full</span></a></p>
<p><span style="font-weight: 400;">Lin Hui-Hsien, Farkas Michelle E.Altered Circadian Rhythms and Breast Cancer: From the Human to the Molecular Level  </span></p>
<p><i><span style="font-weight: 400;">Frontiers in Endocrinology</span></i><span style="font-weight: 400;"> VOLUME=9   2018  10.3389/fendo.2018.00219   ISSN=1664-2392 </span></p>
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		<title>Reflecting on Precision Life: A Year-End Review</title>
		<link>https://precisionhealthalliance.org/reflecting-on-precision-life-a-year-end-review/</link>
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		<dc:creator><![CDATA[Melinda Perkins]]></dc:creator>
		<pubDate>Thu, 14 Dec 2023 17:48:59 +0000</pubDate>
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					<description><![CDATA[By Melinda Perkins &#8211; As we stand on the precipice of this year&#8217;s end and next year’s beginning it’s natural to pause, take a breath and look over our shoulder [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>By Melinda Perkins &#8211;</p>
<p><span style="font-weight: 400;">As we stand on the precipice of this year&#8217;s end and next year’s beginning it’s natural to pause, take a breath and look over our shoulder at the path we’ve traversed. Across the year here at PHA, each month we’ve explored a different landscape that, when put together, defines the overall quality of our Precision Life. Let&#8217;s take a moment to journey through the highlights and lessons, examining the topography of our experiences.</span></p>
<h2><span style="font-weight: 400;">Happiness: The Landscape of Joy </span></h2>
<p><span style="font-weight: 400;">Whether it&#8217;s a triumphant client WIN, a cherished family event, or a professional milestone, the elements which define our happy moments are biologically and psychologically based. This makes them personal at a molecular level.Take a stroll down memory lane by scrolling through the photos on your phone – a visual diary of joy and accomplishment. Reflect on the landscape of happiness. What does it look like for you? Where were you? Who were you with? What were you doing in those most vibrant moments?</span></p>
<h2><span style="font-weight: 400;">Environment: The Nourishing Petri Dish of Well-being</span></h2>
<p><span style="font-weight: 400;">Our surroundings influence us on a biological level, turning genes off and on by the moment and across the days, weeks, months. Pause and consider the spaces, people, and places that shaped your daily life. How did they support you, challenge you, change you; silently sculpting your experiences?</span></p>
<h2><span style="font-weight: 400;">Genius: The Forest of Your Biologically Predisposed Strengths</span></h2>
<p><span style="font-weight: 400;">Your neurons fire and wire and your hormones ebb and flow, continuously crafting and supporting your natural gifts. This is the internal scene that sets you apart from every other person on the planet. Reflect on the skills, talents and abilities that make you shine in your industry and your community. Recognizing and leaning into your expertise is the key to continuous growth and fulfillment.  </span></p>
<h2><span style="font-weight: 400;">Learning: The Terrain of Your Knowledge, Your Way</span></h2>
<p><span style="font-weight: 400;">Who you are on a cellular level, right through to the chemicals that surge through your tissues and the way your muscles move in response to stimuli determines what methods of information absorption work best for you. From lessons learned to skills acquired, consider how you leaned into your biological strengths to expedite learning and retain information longer. What settings, structures, protocols and subjects defined the topography of your knowledge acquisition?</span></p>
<h2><span style="font-weight: 400;">Love:  The Scene of Connection and Communication </span></h2>
<p><span style="font-weight: 400;">From the care we take with ourselves to the way we engage with other people, places, situations and things, how we love is biologically unique to us. Who were the clients that brought a smile to your face? What colleagues did you connect with? How did you deepen your relationships with those close to you? What skills did you level-up, places did you explore and things did you acquire? These elements combine to craft your specific landscape of love.</span></p>
<h2><span style="font-weight: 400;">Stress: Settings that Evolve Strength</span></h2>
<p><span style="font-weight: 400;">It’s tempting to define our lives by the stressors we encounter, conquer and succumb to. Instead, challenge yourself to look at the methods, timings and modalities which help you naturally flow through life’s peaks and valleys. When do you feel bulletproof? How do you intentionally add stress to spur growth and resilience? What activities increase your zen? Evaluate the elements of your ideal stress habitat. </span></p>
<h2><span style="font-weight: 400;">Sleep: The Land Where Chronobiology is King</span></h2>
<p><span style="font-weight: 400;">Sleep quality sets the scene for life. Being rested or not largely determines how you experience the world, interact with what it tosses your way and work out ways to craft your future. The formations in our best sleep terrain are largely decided before birth. Your chronobiological rhythms, daily energy flow and natural brain states are biologically and psychologically unique to you. Whether you assess the data from your wearable, flip back through the pages of your dream journal or simply reflect on your sleep habits and hygiene, sweep your eyes across what constructs support your ability to rest. </span></p>
<h2><span style="font-weight: 400;">Mental Health: Waves of Thought, Gales of Feelings</span></h2>
<p><span style="font-weight: 400;">From feeding our brains to working them properly to getting in that perfect brain state for flowy functionality, mental health incorporates a vast vista of biological predispositions and lifestyle choices. Take a look at yours. When does your brain feel in peak form? When have you felt the most ease, the best equipped to handle a curve-ball, and the clearest about your past, present and future? Look across the landscape of your best mental health and see where peace prevails.</span></p>
<h2><span style="font-weight: 400;">Lifestyle: The Territory of Habits, Fiascos and Routines</span></h2>
<p><span style="font-weight: 400;">Like rearranging the elements of our backyard for optimal practicality and pleasure, we can adjust the components of our lifestyle to align with our biology and psychology for top flow. Consider your daily, weekly and monthly practices and patterns. Where did you thrive? Where did your energy, vitality and enjoyment fall flat? It’s a balancing act that is intensely personal. The facets that you pull forward and those you push into the background will suit your specific genius, desires and intentions.</span></p>
<h2><span style="font-weight: 400;">Mindfulness: The Property of Presence</span></h2>
<p><span style="font-weight: 400;">When you gaze across the panorama of your mindful moments, how you collected them will be as specific to you as the contents they encompass. The only similarities with anyone else on the planet is the way they impact your life. In the chaos of the health industry, mindfulness emerges as a powerful tool to maintain the level of professionalism and decorum you need to support your clients. Explore your mindfulness techniques across the year and the ways they brought focus and serenity to your daily life.</span></p>
<h2><span style="font-weight: 400;">Fitness: Moving Mountains</span></h2>
<p><span style="font-weight: 400;">From the way each one of your 600 muscles is shaped to how they attach to the bones and move your limbs, everything about your physical body is unique to you. Naturally, then, the way you build strength, the times when you have the most stamina, the methods you use to recover are all precisely tuned to you, too. As you glance back across the landmarks of your fitness scenario, ask these things: Did you play up what your body is built for? How well did you utilize the stress and recovery cycles to optimize your biological strengths for a healthier, more resilient you?</span></p>
<h2><span style="font-weight: 400;">Food: Fuel for Life</span></h2>
<p><span style="font-weight: 400;">Do you cringe at the word ‘diet’ or recognize that it’s simply a way of life? Your way of life, just as every other aspect we have discussed, is distinctly your own. What you ingest has no more or no less significance than any of the other factors. With this lens, gaze across the scene of your yearly nutrition. How did you place your meals and the contents of your plates, cups and bowls to keep your body and mind running with powerful precision? Reflect on what worked well and explore opportunities for nourishment that align with your individuality.</span></p>
<p><span style="font-weight: 400;">When you’ve taken in all the nuances of the well-trodden path behind you and cast your eyes forward once again to the crossroads before you, we hope what you see is more vivid and detailed.  The brilliance of your individuality will light the way to a life more precisely tailored to your needs and a future filled with purpose, growth, and success. This is the Precision Life!</span></p>
<p><span style="font-weight: 400;">If you’re interested in </span><span style="font-weight: 400;">learning how to apply precision methods and technology solutions to your service offering check out our</span><a href="https://precisionhealthalliance.org/course-pha-level-1/"><span style="font-weight: 400;"> Level 1 Course for Health Professionals</span></a></p>
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